Histomorphological and clinicopathological correlates of reflux esophagitis

Barrett's esophagus, reflux esophagitis, and eosinophilic esophagitis.

o r t R s h m f 3 o b Many new and exciting endoscopy-related studies on Barrett’s esophagus, reflux esophagitis, and eosinophilic esophagitis were presented during the 2012 Digestive Disease Week (DDW; 19-22 May, San Diego, California, USA). Endoscopic research in Barrett’s esophagus mainly focused on surveillance, detection, and ablation therapy, while clinical studies in eosinophilic esophag...

Reflux esophagitis and Barrett's esophagus.

Histomorphological and Immunophenotypic Features of Pill-Induced Esophagitis

The aim of this study was to investigate histomorphological and immunophenotypic features in pill-induced esophagitis. We comparatively evaluated the histomorphological, immunophenotypic features of pill-induced esophagitis vs. reflux esophagitis, as well as clinical information and endoscopic findings. Fifty-two tissue pieces from 22 cases of pill-induced esophagitis, 46 pieces from 20 reflux ...

Eosinophilic Esophagitis: A Clinicopathological Review

Eosinophilic esophagitis (EoE) is a chronic, atopic inflammatory disorder of the esophagus. With the escalating prevalence in children and young adults, revised guidelines have been established. Its pathogenesis has been associated with T helper Type 2 (Th2) inflammatory response. Diagnosis is based on a comprehensive evaluation including patient’s clinical manifestations and characteristic his...

Management of refractory and complicated reflux esophagitis.

Simple intermittent heartburn with minor or no esophagitis can be treated with simple measures including lifestyle changes and antacids as needed, or H2 receptor antagonists (H2RA), and has a good outcome. Problematic reflux includes resistance to therapy, stricture, Barrett's esophagus and aspiration. Severe reflux esophagitis, often resistant to H2RA therapy, requires more potent treatment wi...